Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.37 extracted from

  • Abtahi, N.; Shahriari, A.; Talaiezadeh, A.; Fathizadeh, P.
    Kinetic characterization of malate dehydrogenase in normal and malignant human breast tissues (2017), Biomed. Res. (Aligarh), 28, 4329-4334 .
No PubMed abstract available
Search for more literature for 1.1.1.37

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.43
-
 NAD+ enzyme from normal breast tissue, at pH 8.0, temperature not specified in the publication Homo sapiens
0.93
-
 NAD+ enzyme from cancerous breast tissue, at pH 8.0, temperature not specified in the publication Homo sapiens
1.6
-
 (S)-malate enzyme from cancerous breast tissue, at pH 8.0, temperature not specified in the publication Homo sapiens
3.13
-
 (S)-malate enzyme from normal breast tissue, at pH 8.0, temperature not specified in the publication Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-malate + NAD+ Homo sapiens
-
 oxaloacetate + NADH + H+
-
 r
oxaloacetate + NADH + H+ Homo sapiens
-
 (S)-malate + NAD+
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast
-
 Homo sapiens
-
breast cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-malate + NAD+
-
 Homo sapiens oxaloacetate + NADH + H+
-
 r
oxaloacetate + NADH + H+
-
 Homo sapiens (S)-malate + NAD+
-
 r

Synonyms

Synonyms Comment Organism
MDH
-
 Homo sapiens