Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | more effective in the presence of Mn2+ than in the presence of Mg2+, 50% inhibition with 1.6 mM Mn2+ and 3.9 mM in the presence of Mg2+ respectively | Escherichia coli | |
CoA | 50% inhibition with 0.75 mM CoA in the presence of Mg2+ and 3.4 mM in the presence of Mn2+ | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | complex sigmoidal saturation curve of free malate concentration in the presence of 5 mM Mg2+ | Escherichia coli | |
Mn2+ | hyperbolic saturation curve of free malate concentration in the presence of 0.3 mM Mn2+ | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | Escherichia coli | - |
CO2 + pyruvate + NADH | - |
? | |
Oxaloacetate | Escherichia coli | - |
CO2 + pyruvate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NAD+ | - |
Escherichia coli | CO2 + pyruvate + NADH | - |
? | |
(S)-malate + NAD+ | - |
Escherichia coli | CO2 + pyruvate + NADH | - |
r | |
Oxaloacetate | - |
Escherichia coli | CO2 + pyruvate | - |
ir |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
- |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Escherichia coli |