Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37732 | - |
1 * 38000, SDS-PAGE, 1 * 37732, calculated, His-tagged recombinant protein | Saccharopolyspora spinosa |
38000 | - |
gel filtration | Saccharopolyspora spinosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
TDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ | Saccharopolyspora spinosa | - |
TDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharopolyspora spinosa | Q9ALN5 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
TDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ | - |
Saccharopolyspora spinosa | TDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 38000, SDS-PAGE, 1 * 37732, calculated, His-tagged recombinant protein | Saccharopolyspora spinosa |
Synonyms | Comment | Organism |
---|---|---|
SpnN | - |
Saccharopolyspora spinosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | NADPH is preferred over NADH | Saccharopolyspora spinosa | |
NADPH | preferred over NADH | Saccharopolyspora spinosa |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme is involved in insecticide spinosyn synthesis. It acts sequentially with 2,3-dehydratase SpnO to catalyze C-2 deoxygenation of TDP-4-dehydro-6-deoxy-D-glucose to form the SpnQ substrate, TDP-4-dehydro-2,6-dideoxy-D-glucose | Saccharopolyspora spinosa |