Literature summary for 1.1.1.4 extracted from

de Oliveira, R.R.; Nicholson, W.L.
Synthetic operon for (R,R)-2,3-butanediol production in Bacillus subtilis and Escherichia coli (2016), Appl. Microbiol. Biotechnol., 100, 719-728.

Search for more literature for 1.1.1.4

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Bacillus subtilis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
37000	-	-	Bacillus subtilis
40000	-	x * 40000, SDS-PAGE	Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(R,R)-butane-2,3-diol + NAD+	Bacillus subtilis	-	(R)-acetoin + NADH + H+	-	?
(R,R)-butane-2,3-diol + NAD+	Bacillus subtilis WN1038	-	(R)-acetoin + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	-	-	-
Bacillus subtilis WN1038	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(R,R)-butane-2,3-diol + NAD+	-	Bacillus subtilis	(R)-acetoin + NADH + H+	-	?
(R,R)-butane-2,3-diol + NAD+	-	Bacillus subtilis WN1038	(R)-acetoin + NADH + H+	-	?

Subunits

Subunits	Comment	Organism
?	x * 40000, SDS-PAGE	Bacillus subtilis
?	x * 37000, calculated from amino acid sequence	Bacillus subtilis

Synonyms

Synonyms	Comment	Organism
BdhA	-	Bacillus subtilis

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Bacillus subtilis

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Release 2023.1 (January 2023)