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Literature summary for 1.1.1.41 extracted from

  • Huang, Y.C.; Kumar, A.; Colman, R.F.
    Identification of the subunits and target peptides of pig heart NAD-specific isocitrate dehydrogenase modified by the affinity label 8-(4-bromo-2,3-dioxobutylthio)NAD (1997), Arch. Biochem. Biophys., 348, 207-218.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
ADP
-
Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Sus scrofa
Mn2+
-
Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NAD+ Sus scrofa
-
2-oxoglutarate + CO2 + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
8-(4-bromo-2,3-dioxobutylthio)-NAD+ + isocitrate
-
Sus scrofa 2-oxoglutarate + CO2 + 8-(4-bromo-2,3-dioxobutylthio)-NADH
-
?
isocitrate + NAD+
-
Sus scrofa 2-oxoglutarate + CO2 + NADH + H+
-
?

Subunits

Subunits Comment Organism
tetramer alpha2betagamma, 4 * 39000-41000, SDS-PAGE Sus scrofa

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Sus scrofa