Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.41 extracted from

  • Sienkiewicz-Porzucek, A.; Sulpice, R.; Osorio, S.; Krahnert, I.; Leisse, A.; Urbanczyk-Wochniak, E.; Hodges, M.; Fernie, A.R.; Nunes-Nesi, A.
    Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth (2010), Mol. Plant, 3, 156-173.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.1.41

Cloned(Commentary)

Cloned (Comment) Organism
gene SlIDH1, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in antisense orientation in tomato plants Solanum lycopersicum

Protein Variants

Protein Variants Comment Organism
additional information transgenic tomato plants expressing the IDH gene in antisense orientation display a mild reduction in the activity of the target enzyme in the leaves but essentially no visible alteration in growth from the wild-type. Fruit size and yield are, however, reduced Solanum lycopersicum

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Solanum lycopersicum 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
isocitrate + NAD+ Solanum lycopersicum
-
 2-oxoglutarate + NADH + H+ + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Solanum lycopersicum
-
 gene SlIDH1
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isocitrate + NAD+
-
 Solanum lycopersicum 2-oxoglutarate + NADH + H+ + CO2
-
 ?

Synonyms

Synonyms Comment Organism
IDH1
-
 Solanum lycopersicum
mIDH
-
 Solanum lycopersicum
mitochondrial NAD-dependent isocitrate dehydrogenase
-
 Solanum lycopersicum
NAD-Dependent IDH
-
 Solanum lycopersicum

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Solanum lycopersicum

General Information

General Information Comment Organism
additional information reduction of mitochondrial IDH activity has little effect on the relative electron transport or assimilation rates and a minor reduction in the maximum efficiency of PSII Solanum lycopersicum