Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | substrate inhibition | Aspergillus niger | |
ATP | - |
Aspergillus niger | |
citrate | - |
Aspergillus niger | |
glyoxylate | plus oxaloacetate | Aspergillus niger | |
NADPH | - |
Aspergillus niger |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Aspergillus niger | 5737 | - |
cytoplasm | - |
Phycomyces blakesleeanus | 5737 | - |
cytoplasm | - |
Blastocladiella emersonii | 5737 | - |
mitochondrion | - |
Aspergillus niger | 5739 | - |
mitochondrion | - |
Phycomyces blakesleeanus | 5739 | - |
mitochondrion | - |
Blastocladiella emersonii | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | absolute requirement for divalent cations | Aspergillus niger | |
Mn2+ | absolute requirement for divalent cations | Aspergillus niger |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
PAGE | Aspergillus niger |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
isocitrate + NADP+ | Aspergillus niger | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
isocitrate + NADP+ | Phycomyces blakesleeanus | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
isocitrate + NADP+ | Blastocladiella emersonii | - |
2-oxoglutarate + NADPH + H+ + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus niger | - |
- |
- |
Blastocladiella emersonii | - |
- |
- |
Phycomyces blakesleeanus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Aspergillus niger |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
14.4 | - |
- |
Aspergillus niger |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isocitrate + NADP+ | - |
Aspergillus niger | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
isocitrate + NADP+ | - |
Phycomyces blakesleeanus | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? | |
isocitrate + NADP+ | - |
Blastocladiella emersonii | 2-oxoglutarate + NADPH + H+ + CO2 | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
28 | - |
- |
Aspergillus niger |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 8 | - |
Aspergillus niger |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.3 | 7.8 | - |
Aspergillus niger |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Aspergillus niger | |
NADP+ | - |
Phycomyces blakesleeanus | |
NADP+ | - |
Blastocladiella emersonii |