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Literature summary for 1.1.1.42 extracted from

  • Shin, S.W.; Kil, I.S.; Park, J.W.
    Silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase by small interfering RNA enhances heat shock-induced apoptosis (2008), Biochem. Biophys. Res. Commun., 366, 1012-1018.
    View publication on PubMed

Application

Application Comment Organism
medicine sensitizing effect of NADP+-dependent isocitrate dehydrogenase siRNA on the apoptotic cell death of HeLa cells offers the possibility of developing a modifier of cancer therapy Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens NADP+-dependent isocitrate dehydrogenase may play an important role in regulating the apoptosis induced by heat shock ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens P48735
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Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell silencing of NADP+-dependent isocitrate dehydrogenase expression in HeLa cells greatly enhances apoptosis induced by heat shock Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information NADP+-dependent isocitrate dehydrogenase may play an important role in regulating the apoptosis induced by heat shock Homo sapiens ?
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?

Synonyms

Synonyms Comment Organism
NADP+-dependent isocitrate dehydrogenase
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Homo sapiens