Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | ischemia-reperfusion significantly reduces IDPc expression and activity | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
47000 | - |
SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | IDPc expression and activity is highest in the cortex, modest in the outer medulla and lowest in the inner medulla, IDPc is also highly expressed in the mitochondrion-rich intercalatal cells of the collecting duct | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
threo-Ds-isocitrate + NADP+ | - |
Mus musculus | 2-oxoglutarate + CO2 + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cytosolic NADP+-dependent isocitrate dehydrogenase | - |
Mus musculus |
IDPc | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Mus musculus |