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Literature summary for 1.1.1.43 extracted from

  • Ciftci, M.; Yilmaz, H.; Coban, T.A.; Gul, M.; Gumustekin, K.; Dane, S.
    Effects of nicotine and vitamin E on 6-phosphogluconate dehydrogenase activity in some rat tissues in vivo and in vitro (2008), J. Enzyme Inhib. Med. Chem., 23, 261-265.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information nicotine activates the muscle, lungs, and testicular 6PGD enzyme activity but has no effect on heart and liver 6PGD activity, when nicotine is administered with vitamin E the increase in 6PGD enzyme activity in muscle and testicles are lower, vitamin E may favourably increase 6PGD enzyme activity in liver in nicotine treated rats, while it has negligible effects on this enzyme activity in other tissues Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-
lung
-
Rattus norvegicus
-
muscle
-
Rattus norvegicus
-
testis
-
Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
6-phosphogluconate dehydrogenase
-
Rattus norvegicus
6PGD
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Rattus norvegicus