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Literature summary for 1.1.1.45 extracted from

  • Menotti-Raymond, M.; Sullivan, D.T.
    Further characterization of L-beta-hydroxyacid dehydrogenase from Drosophila (1985), Biochim. Biophys. Acta, 841, 15-21.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
66000 70000 33000/unit in vitro, 35000/unit in vivo, SDS-PAGE Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-gulonic acid + NAD+ Drosophila melanogaster
-
3-dehydro-L-gulonic acid + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
no modification
-
Drosophila melanogaster

Purification (Commentary)

Purification (Comment) Organism
12%-52% yield Drosophila melanogaster

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
21
-
-
Drosophila melanogaster
63.8
-
-
Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-gulonic acid + NAD+
-
Drosophila melanogaster 3-dehydro-L-gulonic acid + NADH + H+
-
?
L-gulonic acid + NAD+
-
Drosophila melanogaster 3-dehydro-L-gulonic acid + NADH + H+
-
r

Subunits

Subunits Comment Organism
dimer alpha2, 2 * 33000-35000, SDS-PAGE Drosophila melanogaster

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Drosophila melanogaster
NADH
-
Drosophila melanogaster