Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, chromosome metaphase, interphase mapping, i.e. FISH mapping, localization on chromosome 10q11.2, stable expression in HEK-293 cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrotestosterone + NADPH + H+ | Homo sapiens | androsterone inactivation | 5alpha-androstane-3beta,17beta-diol + NADP+ | - |
? | |
estrone + NADPH | Homo sapiens | estrogen activation | estradiol + NADP+ | - |
? | |
additional information | Homo sapiens | the isozyme might play an imporant role in modulation of active hormone levels in estrogen-sensitive cells or tissues | ? | - |
? | |
zymosterone + NADPH | Homo sapiens | - |
zymosterol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydrotestosterone + NADPH + H+ | androsterone inactivation | Homo sapiens | 5alpha-androstane-3beta,17beta-diol + NADP+ | - |
? | |
estrone + NADPH | estrogen activation | Homo sapiens | estradiol + NADP+ | - |
? | |
additional information | the isozyme might play an imporant role in modulation of active hormone levels in estrogen-sensitive cells or tissues | Homo sapiens | ? | - |
? | |
zymosterone + NADPH | - |
Homo sapiens | zymosterol + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD7_2 | - |
Homo sapiens |
form 2 type 7 17beta-hydroxysteroid dehydrogenase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |