Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17-Acetoxyprogesterone | - |
Streptomyces exfoliatus | |
17-Bromoacetoxyprogesterone | - |
Streptomyces exfoliatus | |
5alpha-Dihydrotestosterone bromoacetate | - |
Streptomyces exfoliatus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0039 | - |
progesterone | - |
Streptomyces exfoliatus | |
0.0045 | - |
5alpha-pregnane-3,20-dione | - |
Streptomyces exfoliatus | |
0.0105 | - |
17-hydroxyprogesterone | - |
Streptomyces exfoliatus | |
0.02 | - |
6beta-[bromoacetoxy]-progesterone | - |
Streptomyces exfoliatus | |
0.318 | - |
cortisone | - |
Streptomyces exfoliatus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces exfoliatus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Streptomyces exfoliatus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17-hydroxyprogesterone + NADH | - |
Streptomyces exfoliatus | ? | - |
? | |
17alpha-hydroxyprogesterone + NADPH + H+ | - |
Streptomyces exfoliatus | 17alpha,20beta-dihydroxy-pregn-4-ene-3-one + NADP+ | - |
? | |
5alpha-pregnane-3,20-dione + NADH | - |
Streptomyces exfoliatus | ? | - |
? | |
6beta-(bromoacetoxy)-progesterone + NADH | - |
Streptomyces exfoliatus | ? | - |
? | |
6beta-[bromoacetoxy]-progesterone + NAD+ | - |
Streptomyces exfoliatus | ? | - |
r | |
cortisone + NAD(P)H | i.e. 17beta,21-dihydroxy-pregn-4-ene-3,11,20-trione | Streptomyces exfoliatus | 17alpha,20beta,21-trihydroxy-pregn-4-ene-3,11-dione + NAD(P)+ | - |
? | |
progesterone + NAD(P)H | - |
Streptomyces exfoliatus | 20beta-hydroxy-pregn-4-ene-3-one + NAD(P)+ | - |
? |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
9 | - |
in Tris-buffer, best value for stability | Streptomyces exfoliatus |