Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | Homo sapiens | final step in the synthesis of active estrogens | estradiol-17beta + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
isoform 1, 17HSD1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast | - |
Homo sapiens | - |
cytotrophoblast | cultured cells, enzyme expression is stimulated with all-trans and 9-cis retinoic acid | Homo sapiens | - |
JEG-3 cell | cultured cells, enzyme expression is stimulated with all-trans and 9-cis retinoic acid | Homo sapiens | - |
placenta | - |
Homo sapiens | - |
T-47D cell | cultured cells | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | - |
Homo sapiens | estradiol-17beta + NADP+ | - |
? | |
estrone + NADPH + H+ | final step in the synthesis of active estrogens | Homo sapiens | estradiol-17beta + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |