Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5alpha-dihydrotestosterone + NADP+ | Homo sapiens | the enzyme could play a critical role in estrogen-sensitive cells, since it inactivates 5alpha-dihydrotestosterone that generally shows antagonistic effect in the cells | 5alpha-androstan-3,17-dione + NADPH | - |
? | |
estrone + NAD(P)H | Homo sapiens | the enzyme produces active estradiol for cell proliferation | estradiol-17beta + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q5MGS6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
prostate gland | - |
Homo sapiens | - |
uterus | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5alpha-dihydrotestosterone + NADP+ | - |
Homo sapiens | 5alpha-androstan-3,17-dione + NADPH | - |
? | |
5alpha-dihydrotestosterone + NADP+ | the enzyme could play a critical role in estrogen-sensitive cells, since it inactivates 5alpha-dihydrotestosterone that generally shows antagonistic effect in the cells | Homo sapiens | 5alpha-androstan-3,17-dione + NADPH | - |
? | |
estrone + NAD(P)H | the enzyme produces active estradiol for cell proliferation | Homo sapiens | estradiol-17beta + NAD(P)+ | - |
? | |
estrone + NAD(P)H + H+ | - |
Homo sapiens | estradiol-17beta + NAD(P)+ | - |
? | |
zymosterone + NAD(P)H | - |
Homo sapiens | zymosterol + NAD(P)+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD7 2 | - |
Homo sapiens |
form 2 type 7 17beta-hydroxysteroid dehydrogenase | - |
Homo sapiens |