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Literature summary for 1.1.1.64 extracted from

  • Villee, C.A.; Spencer, J.M.
    Some properties of the pyridine nucleotide-specific 17beta-hydroxy steroid dehydrogenases of guinea pig liver (1960), J. Biol. Chem., 235, 3615-3619.
    View publication on PubMed
Search for more literature for 1.1.1.64

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.011
-
 NADP+
-
 Cavia porcellus
0.27
-
 testosterone
-
 Cavia porcellus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Cavia porcellus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
17beta-estradiol + NADP+ Cavia porcellus
-
 estrone + NADPH
-
 r
testosterone + NADP+ Cavia porcellus
-
 androst-4-ene-3,17-dione + NADPH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate, calcium phosphate gel, starch electrophoresis Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Cavia porcellus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
145
-
-
 Cavia porcellus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17beta-estradiol + NADP+
-
 Cavia porcellus estrone + NADPH
-
 r
testosterone + NADP+
-
 Cavia porcellus androst-4-ene-3,17-dione + NADPH + H+
-
 r

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
57
-
 complete inactivation after 15 min Cavia porcellus

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Cavia porcellus