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Literature summary for 1.1.1.85 extracted from

  • Nozawa, A.; Takano, J.; Miwa, K.; Nakagawa, Y.; Fujiwara, T.
    Cloning of cDNAs encoding isopropylmalate dehydrogenase from Arabidopsis thaliana and accumulation patterns of their transcripts (2005), Biosci. Biotechnol. Biochem., 69, 806-810.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
genes IMD1, IMD2, and IMD3, DNA and amino acid sequence determination and analysis, expression analysis, complementation of the deficient Saccharomyces cerevisiae strain BY4741 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast the enzyme contains a transit peptide Arabidopsis thaliana 9507
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-isopropylmalate + NAD+ Arabidopsis thaliana the enzyme catalyzes a step in leucine biosynthesis 2-ketoisocaproate + CO2 + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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ecotype Col-1, genes IMD1, IMD2, and IMD3
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Source Tissue

Source Tissue Comment Organism Textmining
cauline leaf high expression level of IMD3 and IMD2 Arabidopsis thaliana
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flower very low expression level of IMD1 Arabidopsis thaliana
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additional information tissue specific expression of genes IMD1, IMD2, and IMD3, overview Arabidopsis thaliana
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root high expression level of IMD1 and IMD2 Arabidopsis thaliana
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rosette leaf high expression level of IMD3 and IMD2 Arabidopsis thaliana
-
stem
-
Arabidopsis thaliana
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-isopropylmalate + NAD+
-
Arabidopsis thaliana 2-ketoisocaproate + CO2 + NADH + H+
-
?
3-isopropylmalate + NAD+ the enzyme catalyzes a step in leucine biosynthesis Arabidopsis thaliana 2-ketoisocaproate + CO2 + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
IPMDH
-
Arabidopsis thaliana
isopropylmalate dehydrogenase
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Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Arabidopsis thaliana