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Literature summary for 1.1.1.9 extracted from

  • Toivari, M.H.; Ruohonen, L.; Miasnikov, A.N.; Richard, P.; Penttila, M.
    Metabolic engineering of Saccharomyces cerevisiae for conversion of D-glucose to xylitol and other five-carbon sugars and sugar alcohols (2007), Appl. Environ. Microbiol., 73, 5471-5476.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in transketolase-deficient Saccharomyces cerevisiae strain (W303/tkl1 tkl2/2C) Scheffersomyces stipitis

Protein Variants

Protein Variants Comment Organism
additional information expression of the xylitol dehydrogenase-encoding gene XYL2 of Pichia stipitis in the transketolase-deficient Saccharomyces cerevisiae strain results in an 8.5fold enhancement of the total amount of the excreted sugar alcohols ribitol and xylitol. The additional introduction of the 2-deoxy-glucose 6-phosphate phosphatase-encoding gene DOG1 into the transketolase-deficient strain expressing the XYL2 gene resulted in a further 1.6fold increase in ribitol production Scheffersomyces stipitis

Organism

Organism UniProt Comment Textmining
Scheffersomyces stipitis
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-
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Synonyms

Synonyms Comment Organism
XYL2
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Scheffersomyces stipitis
xylitol dehydrogenase
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Scheffersomyces stipitis