Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.B3 extracted from

  • Koesoema, A.A.; Sugiyama, Y.; Sriwong, K.T.; Xu, Z.; Verina, S.; Standley, D.M.; Senda, M.; Senda, T.; Matsuda, T.
    Reversible control of enantioselectivity by the length of ketone substituent in biocatalytic reduction (2019), Appl. Microbiol. Biotechnol., 103, 9529-9541 .
    View publication on PubMed
Search for more literature for 1.1.1.B3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rosetta(DE3) cells Geotrichum candidum

Protein Variants

Protein Variants Comment Organism
W288A (R)-selective mutant Geotrichum candidum
W288I (R)-selective mutant Geotrichum candidum
W288L the enantiopreference oft he mutant is intermediate between wild type (S)-selectivity and (R)-selectivity Geotrichum candidum
W288M the enantiopreference of the mutant enzyme is similar to wild type ((S)-selectivity) Geotrichum candidum
W288V (R)-selective mutant Geotrichum candidum

Organism

Organism UniProt Comment Textmining
Geotrichum candidum M5A8V4
-
-
Geotrichum candidum NBRC 4597 M5A8V4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phenylbutan-1-one + NADH + H+
-
 Geotrichum candidum 1-phenylbutan-1-ol + NAD+
-
 ?
1-phenylbutan-1-one + NADH + H+
-
 Geotrichum candidum NBRC 4597 1-phenylbutan-1-ol + NAD+
-
 ?
1-phenylheptan-1-one + NADH + H+
-
 Geotrichum candidum 1-phenylheptan-1-ol + NAD+
-
 ?
1-phenylheptan-1-one + NADH + H+
-
 Geotrichum candidum NBRC 4597 1-phenylheptan-1-ol + NAD+
-
 ?
1-phenylhexan-1-one + NADH + H+
-
 Geotrichum candidum 1-phenylhexan-1-ol + NAD+
-
 ?
1-phenylhexan-1-one + NADH + H+
-
 Geotrichum candidum NBRC 4597 1-phenylhexan-1-ol + NAD+
-
 ?
1-phenylpentan-1-one + NADH + H+
-
 Geotrichum candidum 1-phenylpentan-1-ol + NAD+
-
 ?
1-phenylpropan-1-one + NADH + H+
-
 Geotrichum candidum 1-phenylpropan-1-ol + NAD+
-
 ?
3-heptanone + NADH + H+
-
 Geotrichum candidum 3-hexanol + NADH + H+
-
 ?
acetophenone + NADH + H+
-
 Geotrichum candidum (1S)-1-phenylethanol + NAD+
-
 ?
acetophenone + NADH + H+
-
 Geotrichum candidum NBRC 4597 (1S)-1-phenylethanol + NAD+
-
 ?
heptan-2-one + NADH + H+
-
 Geotrichum candidum heptan-2-ol + NAD+
-
 ?
heptan-3-one + NADH + H+
-
 Geotrichum candidum heptan-3-ol + NAD+
-
 ?
heptan-4-one + NADH + H+
-
 Geotrichum candidum heptan-4-ol + NAD+
-
 ?
hexan-2-one + NADH + H+
-
 Geotrichum candidum hexan-2-ol + NAD+
-
 ?
hexan-3-one + NADH + H+
-
 Geotrichum candidum hexan-3-ol + NAD+
-
 ?
nonan-2-one + NADH + H+
-
 Geotrichum candidum nonan-2-ol + NAD+
-
 ?
nonan-3-one + NADH + H+
-
 Geotrichum candidum nonan-3-ol + NAD+
-
 ?
nonan-4-one + NADH + H+
-
 Geotrichum candidum nonan-4-ol + NAD+
-
 ?
nonan-5-one + NADH + H+
-
 Geotrichum candidum nonan-5-ol + NAD+
-
 ?
octan-2-one + NADH + H+
-
 Geotrichum candidum octan-2-ol + NAD+
-
 ?
octan-2-one + NADH + H+
-
 Geotrichum candidum NBRC 4597 octan-2-ol + NAD+
-
 ?
octan-3-one + NADH + H+
-
 Geotrichum candidum octan-3-ol + NAD+
-
 ?
octan-4-one + NADH + H+
-
 Geotrichum candidum octan-4-ol + NAD+
-
 ?
pentan-2-one + NADH + H+
-
 Geotrichum candidum pentan-2-ol + NAD+
-
 ?
pentan-3-one + NADH + H+
-
 Geotrichum candidum pentan-3-ol + NAD+
-
 ?

Synonyms

Synonyms Comment Organism
acetophenone reductase
-
 Geotrichum candidum
APRD
-
 Geotrichum candidum
NAD+-dependent ADH
-
 Geotrichum candidum

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Geotrichum candidum