Application | Comment | Organism |
---|---|---|
medicine | both LldD and LldA are important for growth of Pseudomonas aeruginosa PAO1 in synthetic cystic fibrosis sputum medium | Pseudomonas aeruginosa |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Pseudomonas aeruginosa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.336 | - |
L-lactate | pH 7.4, temperature not specified in the publication | Pseudomonas aeruginosa | |
1.102 | - |
L-lactate | pH 7.4, temperature not specified in the publication | Pseudomonas aeruginosa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Pseudomonas aeruginosa | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | Q9HV37 | - |
- |
Pseudomonas aeruginosa | Q9I197 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lactate + 2 ferricytochrome c | - |
Pseudomonas aeruginosa | pyruvate + 2 ferrocytochrome c + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lldA | - |
Pseudomonas aeruginosa |
LldD | - |
Pseudomonas aeruginosa |
PA4771 | - |
Pseudomonas aeruginosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | - |
Pseudomonas aeruginosa |
General Information | Comment | Organism |
---|---|---|
physiological function | disruption of the lldD gene impairs the growth of this strain in L-lactate, but the mutant strain is still able to grow after a long lag phase. Deletion of both the LldD and LldA genes completely impairs the L-lactate utilization capacity of the strain | Pseudomonas aeruginosa |
physiological function | loss of LldA has little effect on L-lactate utilization. Deletion of both the LldD and LldA genes completely impairs the L-lactate utilization capacity of the strain | Pseudomonas aeruginosa |