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Literature summary for 1.1.2.4 extracted from

  • Nygaard, A.P.
    Lactate dehydrogenases of yeast (1963), The Enzymes, 2nd Ed (Boyer, P. D. , Lardy, H. , Myrbäck, K. , eds. ), 7, 557-565.
No PubMed abstract available
Search for more literature for 1.1.2.4

Inhibitors

Inhibitors Comment Organism Structure
high ionic strength
-
 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ inhibitory Saccharomyces cerevisiae
ferricyanide can substitute for cytochrome c Saccharomyces cerevisiae
Mg2+ inhibitory Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-lactate + 2 ferricytochrome c Saccharomyces cerevisiae
-
 pyruvate + ferrocytochrome c
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-lactate + 2 ferricytochrome c
-
 Saccharomyces cerevisiae pyruvate + ferrocytochrome c
-
 ?
(R)-lactate + ferricytochrome c
-
 Saccharomyces cerevisiae pyruvate + ferrocytochrome c
-
 ?
D-2-hydroxybutyrate + cytochrome c
-
 Saccharomyces cerevisiae 2-oxobutanoate + ferrocytochrome c
-
 ?
D-2-hydroxyvalerate + cytochrome c very poor substrate Saccharomyces cerevisiae 2-oxovalerate + ferrocytochrome c
-
 ?

Cofactor

Cofactor Comment Organism Structure
2,6-dichlorophenolindophenol can substitute for cytochrome c Saccharomyces cerevisiae
cytochrome c highly specific Saccharomyces cerevisiae
FAD
-
 Saccharomyces cerevisiae
phenazine methosulfate can substitute for cytochrome c Saccharomyces cerevisiae