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Literature summary for 1.1.3.6 extracted from
- Determination of in vitro and in vivo immune response to recombinant cholesterol oxidase from Mycobacterium tuberculosis (2020), Immunol. Lett., 228, 103-111 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycobacterium tuberculosis | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CHOD | - |
Mycobacterium tuberculosis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme that is involved but is dispensable in the process of cholesterol degradation by Mycobacterium tuberculosis | Mycobacterium tuberculosis |
| physiological function | the enzyme (ChoD) is a virulence factor of Mycobacterium tuberculosis, and it strongly modulates the function of human macrophages in vitro, allowing the intracellular survival of bacteria. It is an active protein, which is able to induce the immune response both in vivo and in vitro | Mycobacterium tuberculosis |
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Release 2023.1 (January 2023)
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