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Literature summary for 1.1.5.2 extracted from

  • Reddy, S.Y.; Bruice, T.C.
    Mechanism of glucose oxidation by quinoprotein soluble glucose dehydrogenase: insights from molecular dynamics studies (2004), J. Am. Chem. Soc., 126, 2431-2438.
    View publication on PubMed
Search for more literature for 1.1.5.2

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm soluble enzyme sGDH Acinetobacter calcoaceticus 5737
-
membrane enzyme mGDH Acinetobacter calcoaceticus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Acinetobacter calcoaceticus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
 2 * 50000, SDS-PAGE Acinetobacter calcoaceticus

Organism

Organism UniProt Comment Textmining
Acinetobacter calcoaceticus
-
 2 enzyme forms, a soluble and a membrane-bound one
-

Reaction

Reaction Comment Organism Reaction ID
D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol catalytic mechanism, His144, Arg228, and Asn229 are involved Acinetobacter calcoaceticus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose + ubiquinone
-
 Acinetobacter calcoaceticus D-glucono-1,5-lactone + ubiquinol
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 50000, SDS-PAGE Acinetobacter calcoaceticus

Synonyms

Synonyms Comment Organism
sGDH
-
 Acinetobacter calcoaceticus
soluble glucose dehydrogenase
-
 Acinetobacter calcoaceticus

Cofactor

Cofactor Comment Organism Structure
pyrroloquinoline quinone i.e. PQQ, or 2,7,9-tricarboxy-1H-pyrrolo [2,3-f]-quinoline-4,5-dione, residues Gln231, Gln246, Ala350, and Leu376 are involved in binding Acinetobacter calcoaceticus

pI Value

Organism Comment pI Value Maximum pI Value
Acinetobacter calcoaceticus
-
-
 9.5