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Literature summary for extracted from

  • Lyon, R.C.; Johnston, S.M.; Panopoulos, A.; Alzeer, S.; McGarvie, G.; Ellis, E.M.
    Enzymes involved in the metabolism of gamma-hydroxybutyrate in SH-SY5Y cells: identification of an iron-dependent alcohol dehydrogenase ADHFe1 (2009), Chem. Biol. Interact., 178, 283-287.
    View publication on PubMed


Organism UniProt Comment Textmining
Homo sapiens Q8IWW8

Source Tissue

Source Tissue Comment Organism Textmining
SH-SY5Y cell
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxybutanoic acid + 2-oxoglutarate
Homo sapiens succinic semialdehyde + D-2-hydroxyglutarate


Synonyms Comment Organism
hydroxyacid-oxoacid transhydrogenase
Homo sapiens
iron-dependent alcohol dehydrogenase ADHFe1
Homo sapiens


Cofactor Comment Organism Structure
NAD(P)+ 2-oxoglutarate serves as an intermediate acceptor to generate NAD(P)H Homo sapiens