Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.10.3.11 extracted from

  • Selinski, J.; Scheibe, R.; Day, D.A.; Whelan, J.
    Alternative oxidase is positive for plant performance (2018), Trends Plant Sci., 23, 588-597 .
    View publication on PubMed
Search for more literature for 1.10.3.11

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Nicotiana tabacum 5739
-
mitochondrion
-
 Macroptilium atropurpureum 5739
-
mitochondrion
-
 Arabidopsis thaliana 5739
-
mitochondrion
-
 Glycine max 5739
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q39219
-
-
Glycine max Q41266
-
-
Glycine max Q7XZQ1
-
-
Macroptilium atropurpureum
-
-
-
Neurospora crassa
-
-
-
Nicotiana tabacum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf AOX2 isoform is most abundant and is constitutively expressed either mainly in photosynthetic tissues (AOX2A) or throughout the whole plant (AOX2D) Macroptilium atropurpureum
-
leaf AOX2 isoform is most abundant and is constitutively expressed either mainly in photosynthetic tissues (AOX2A) or throughout the whole plant (AOX2D) Glycine max
-

Synonyms

Synonyms Comment Organism
AOX
-
 Neurospora crassa
AOX
-
 Nicotiana tabacum
AOX1a
-
 Arabidopsis thaliana
AOX2
-
 Macroptilium atropurpureum
AOX2
-
 Glycine max
AOX2b
-
 Glycine max

Expression

Organism Comment Expression
Arabidopsis thaliana auxin is a strong negative regulator of AtAOX1 a transcript abundance down
Arabidopsis thaliana the transcription factor MYB29 acts as a negative regulator, not directly by binding the AtAOX1a promoter, but rather by crosstalk with a number of hormone signalling pathways that interact with ETHYLENE RESPONSE FACTOR and WRKY transcription factors down
Arabidopsis thaliana WRKY transcription factors 15 and 40 act as negative regulators of AtAOX1a. It is possible that they and other negative regulators are displaced when the latent NAC17 transcription factor is released from the ER upon proteolysis, with subsequent competition for the binding site down
Arabidopsis thaliana cyclin-dependent kinase E1 (CDKE1), a subunit of the mediator complex, is required for induction of AOX1a in Arabidopsis,acting at both a transcriptional and post-transcriptional level up
Arabidopsis thaliana the transcription of AtAOX1a is under strong negative regulation and can be derepressed by activation of the NAC17 transcription factor present in the ER. A variety of ER-bound NAC transcription factors, including NAC13, act downstream of NAC17 to positively regulate AtAOX1a expression. NAC17 is a tail-anchored protein in the ER that must be released by proteolytic cleavage to turn on the expression of AtAOX1a itself and other downstream regulators of AtAOX1a. The transcript abundance of NAC17 is low and not affected by a wide variety of stresses that induce AtAOX1a, and other membrane-bound NAC transcription factors cannot compensate for it. It appears that this positive masterregulator of AOX1a is constitutively expressed at a low level in a latent form and is activated (by proteolytic cleavage on the ER) by mitochondrial dysfunction to turn on AtAOX1a. AtAOX1a is under both negative and positive regulation by WRKY transcription factors that bind to the AtAOX1a promoter up
Neurospora crassa two transcription factors, AOD2 and AOD5, are required for the expression of AOX when the cytochrome pathway is inhibited up

General Information

General Information Comment Organism
malfunction Glycine max antisense lines for AOX2b result in a decrease in photosynthesis rates, altered fertility, and slower vegetative growth Glycine max
physiological function the enzyme is important for plant growth and performance under a variety of stress or adverse growth conditions Nicotiana tabacum
physiological function the enzyme is important for plant growth and performance under a variety of stress or adverse growth conditions. During severe or prolonged mild drought stress in, the amount of AOX protein is important to maintain photosynthetic performance. Enzyme form AOX1a is under strong transcriptional suppression Arabidopsis thaliana
physiological function the enzyme is required for optimal photosynthesis and growth, and gametophyte development Glycine max