Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenine | - |
Gallus sp. | |
adenine | - |
Mus musculus | |
adenine | - |
Ovis aries | |
adenine | - |
Rattus norvegicus | |
ATP | 8% inhibition | Rattus norvegicus | |
CTP | 16% inhibition | Rattus norvegicus | |
cytosine | - |
Gallus sp. | |
cytosine | - |
Mus musculus | |
cytosine | - |
Ovis aries | |
cytosine | - |
Rattus norvegicus | |
dATP | 4% inhibition | Rattus norvegicus | |
dCTP | 20% inhibition | Rattus norvegicus | |
dGTP | 24% inhibition | Rattus norvegicus | |
GTP | 20% inhibition | Rattus norvegicus | |
guanine | - |
Gallus sp. | |
guanine | - |
Mus musculus | |
guanine | - |
Ovis aries | |
guanine | - |
Rattus norvegicus | |
Uracil | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxyanthranilic acid + O2 | Spinacia oleracea | - |
2-amino-2H-isophenoxazine-3-one-1,9-dicarboxylic acid + H2O2 | cinnabarinic acid, oxidative dimerization | ? | |
3-hydroxyanthranilic acid + O2 | Streptomyces antibioticus | - |
2-amino-2H-isophenoxazine-3-one-1,9-dicarboxylic acid + H2O2 | cinnabarinic acid, oxidative dimerization | ? | |
3-hydroxyanthranilic acid + O2 | Trametes coccinea | - |
2-amino-2H-isophenoxazine-3-one-1,9-dicarboxylic acid + H2O2 | cinnabarinic acid, oxidative dimerization | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus sp. | - |
chicken | - |
Mus musculus | - |
mouse, Swiss mice | - |
Ovis aries | - |
sheep | - |
Rattus norvegicus | - |
- |
- |
Spinacia oleracea | - |
spinach | - |
Streptomyces antibioticus | - |
- |
- |
Trametes coccinea | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
leaf | - |
Spinacia oleracea | - |
liver | - |
Mus musculus | - |
liver | - |
Rattus norvegicus | - |
liver | - |
Ovis aries | - |
liver | - |
Gallus sp. | - |
spleen | - |
Rattus norvegicus | - |
thymus | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.03 | - |
thymus tissue, 0.008 M substrate | Rattus norvegicus |
0.034 | - |
thymus tissue, 0.001 M substrate | Rattus norvegicus |
0.037 | - |
spleen tissue, 0.001 M substrate | Rattus norvegicus |
0.047 | - |
thymus tissue, 0.004 M substrate | Rattus norvegicus |
0.07 | - |
regenerating liver | Rattus norvegicus |
0.134 | - |
kidney tissue, 0.001 M substrate | Rattus norvegicus |
0.16 | - |
- |
Mus musculus |
0.185 | - |
- |
Gallus sp. |
0.212 | - |
female | Rattus norvegicus |
0.24 | - |
- |
Ovis aries |
0.25 | - |
liver tissue | Rattus norvegicus |
0.264 | - |
male | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 3-hydroxyanthranilic acid + 2 O2 | - |
Mus musculus | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
2 3-hydroxyanthranilic acid + 2 O2 | - |
Rattus norvegicus | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
2 3-hydroxyanthranilic acid + 2 O2 | - |
Ovis aries | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
2 3-hydroxyanthranilic acid + 2 O2 | - |
Spinacia oleracea | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
2 3-hydroxyanthranilic acid + 2 O2 | - |
Streptomyces antibioticus | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
2 3-hydroxyanthranilic acid + 2 O2 | - |
Gallus sp. | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
2 3-hydroxyanthranilic acid + 2 O2 | - |
Trametes coccinea | 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2 | - |
? | |
3-hydroxyanthranilic acid + O2 | - |
Spinacia oleracea | 2-amino-2H-isophenoxazine-3-one-1,9-dicarboxylic acid + H2O2 | cinnabarinic acid, oxidative dimerization | ? | |
3-hydroxyanthranilic acid + O2 | - |
Streptomyces antibioticus | 2-amino-2H-isophenoxazine-3-one-1,9-dicarboxylic acid + H2O2 | cinnabarinic acid, oxidative dimerization | ? | |
3-hydroxyanthranilic acid + O2 | - |
Trametes coccinea | 2-amino-2H-isophenoxazine-3-one-1,9-dicarboxylic acid + H2O2 | cinnabarinic acid, oxidative dimerization | ? |