Enzymatic oxidation of rifamycins by a microorganism of the genus Humicola

Data extracted from this reference:

Inhibitors

Commentary

Organism

Structure

Fe2+

-

Humicola spp.

Hg2+

-

Humicola spp.

Rifamycin B

concentration above 2 mM

Humicola spp.

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

0.05

-

Rifamycin B

-

Humicola spp.

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

rifamycin B + O2

Humicola spp.

-

rifamycin O + H2O2

-

Humicola spp.

?

Reaction

Commentary

Organism

Reaction ID

rifamycin B + O2 = rifamycin O + H2O2

acts on various kinds of diphenol compounds, converting them into quinonic forms and H2O2

Humicola spp.

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

catechol + O2

-

439884

Humicola spp.

?

-

-

-

?

p-hydroquinone + O2

-

439884

Humicola spp.

?

-

439884

Humicola spp.

?

p-hydroxyphenoxyacetic acid + O2

-

439884

Humicola spp.

?

-

-

-

?

rifamycin B + O2

-

439884

Humicola spp.

rifamycin O + H2O2

-

439884

Humicola spp.

?

rifamycin B + O2

most specific, highest catalytic efficiency

439884

Humicola spp.

rifamycin O + H2O2

-

439884

Humicola spp.

?

rifamycin SV + ?

-

439884

Humicola spp.

?

-

439884

Humicola spp.

?

Inhibitors

Commentary

Organism

Structure

Fe2+

-

Humicola spp.

Hg2+

-

Humicola spp.

Rifamycin B

concentration above 2 mM

Humicola spp.

KM Value [mM]

KM Value Maximum [mM]

Substrate

Commentary

Organism

Structure

0.05

-

Rifamycin B

-

Humicola spp.

Natural Substrates

Organism

Commentary (Nat. Sub.)

Natural Products

Commentary (Nat. Pro.)

Organism (Nat. Pro.)

Reversibility

ID

rifamycin B + O2

Humicola spp.

-

rifamycin O + H2O2

-

Humicola spp.

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

catechol + O2

-

439884

Humicola spp.

?

-

-

-

?

p-hydroquinone + O2

-

439884

Humicola spp.

?

-

439884

Humicola spp.

?

p-hydroxyphenoxyacetic acid + O2

-

439884

Humicola spp.

?

-

-

-

?

rifamycin B + O2

-

439884

Humicola spp.

rifamycin O + H2O2

-

439884

Humicola spp.

?

rifamycin B + O2

most specific, highest catalytic efficiency

439884

Humicola spp.

rifamycin O + H2O2

-

439884

Humicola spp.

?

rifamycin SV + ?

-

439884

Humicola spp.

?

-

439884

Humicola spp.

?

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

688670

Jobanputra

-

Influence of nitrogen sources ...

Chryseobacterium sp.

J. Sci. Ind. Res.

66

615-617

2007

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

1

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

439887

Patil

-

Influence of substrate prepara ...

Curvularia lunata

Indian J. Exp. Biol.

35

917-919

1997

-

1

-

-

-

-

-

-

-

-

-

-

3

1

-

-

-

-

-

-

-

-

1

-

-

1

-

-

-

1

-

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

-

-

-

-

3

-

-

-

-

-

-

-

1

-

1

-

-

-

1

-

-

-

-

-

-

-

-

-

439886

Banerjee

Transformation of rifamycin B ...

Curvularia lunata

Biotechnol. Tech.

7

339-344

1993

-

-

-

-

-

1

-

-

1

-

-

1

-

1

-

-

-

1

-

-

-

-

2

-

-

1

1

4

-

1

1

-

-

-

-

-

-

-

-

-

-

-

1

-

-

-

-

1

-

-

1

-

-

-

-

-

-

-

-

2

-

1

1

4

-

1

1

-

-

-

-

-

-

-

-

439888

Banerjee

Characterization of soluble ri ...

Curvularia lunata

Lett. Appl. Microbiol.

17

1-3

1993

-

1

-

-

-

-

5

1

1

1

-

1

-

7

-

-

1

-

-

-

-

-

1

-

-

1

-

2

-

1

-

-

-

-

-

-

-

1

-

-

-

-

-

-

5

-

1

1

1

-

1

-

-

-

1

-

-

-

-

1

-

1

-

2

-

1

-

-

-

-

-

-

-

-

-

439883

Vohra

-

Microbial transformation of ri ...

Curvularia lunata

Biotechnol. Lett.

11

851-854

1989

-

1

-

-

-

-

-

-

1

-

-

1

-

1

-

-

-

-

-

-

-

-

1

-

-

1

1

-

-

1

1

-

-

-

-

-

-

1

-

-

-

-

-

-

-

-

-

1

-

-

1

-

-

-

-

-

-

-

-

1

-

1

1

-

-

1

1

-

-

-

-

-

-

-

-

439884

Seong

-

Enzymatic oxidation of rifamyc ...

Humicola spp.

J. Ferment. Technol.

63

515-522

1985

-

1

-

-

-

-

3

1

1

1

-

1

-

1

-

-

1

1

-

-

-

1

6

-

-

1

-

-

-

1

-

-

-

-

-

-

-

1

-

-

-

-

-

-

3

-

1

1

1

-

1

-

-

-

1

-

-

-

1

6

-

1

-

-

-

1

-

-

-

-

-

-

-

-

-

439885

Lee

-

The properties of immobilized ...

Humicola spp.

Biotechnol. Lett.

6

143-148

1984

-

1

-

-

-

-

1

2

-

-

-

1

-

1

-

-

-

1

-

-

-

-

1

-

-

2

-

1

-

1

1

-

-

1

-

-

-

1

-

-

-

-

-

-

1

1

2

-

-

-

1

-

-

-

-

-

-

-

-

1

-

2

-

1

-

1

1

-

-

-

-

-

-

-

-

439882

Han

Rifamycin B oxidase from Monoc ...

Monocillium spp.

FEBS Lett.

151

36-40

1983

1

-

-

-

-

-

2

-

-

-

-

1

-

4

-

-

1

1

-

-

1

-

5

-

-

1

-

-

-

1

-

-

1

-

-

-

1

-

-

1

-

-

-

-

2

-

-

-

-

-

1

-

-

-

1

-

-

1

-

5

-

1

-

-

-

1

-

-

-

-

-

-

-

-

-