Data extracted from this reference:
Application
medicine
rifamycin, an ansa-macrolide antibiotic, is used for production of antituberculosic agents
Humicola spp.
Inhibitors
Rifamycin B
concentration above 2 mM
Humicola spp.
KM Value [mM]
0.05
Rifamycin B
Humicola spp.
Localization
intracellular
Humicola spp.
5622
Metals/Ions
additional information
not affected by other metal ions than Fe2+, Hg2+
Humicola spp.
Natural Substrates/ Products (Substrates)
rifamycin B + O2
Humicola spp.
rifamycin O + H2O2
Humicola spp.
?
Organism
Purification (Commentary)
partially, ammonium sulfate precipitation
Humicola spp.
Reaction
rifamycin B + O2 = rifamycin O + H2O2
acts on various kinds of diphenol compounds, converting them into quinonic forms and H2O2
Humicola spp.
Storage Stability
4°C, 100 mM phosphate buffer, pH 7.8, one month, no appreciable loss of actvity
Humicola spp.
Substrates and Products (Substrate)
catechol + O2
439884
Humicola spp.
?
?
p-hydroquinone + O2
439884
Humicola spp.
?
439884
Humicola spp.
?
p-hydroxyphenoxyacetic acid + O2
439884
Humicola spp.
?
?
rifamycin B + O2
439884
Humicola spp.
rifamycin O + H2O2
439884
Humicola spp.
?
rifamycin B + O2
most specific, highest catalytic efficiency
439884
Humicola spp.
rifamycin O + H2O2
439884
Humicola spp.
?
rifamycin SV + ?
439884
Humicola spp.
?
439884
Humicola spp.
?
Temperature Optimum [°C]
45
above the catalytic activity is greatly reduced
Humicola spp.
pH Optimum
Application (protein specific)
medicine
rifamycin, an ansa-macrolide antibiotic, is used for production of antituberculosic agents
Humicola spp.
Inhibitors (protein specific)
Rifamycin B
concentration above 2 mM
Humicola spp.
KM Value [mM] (protein specific)
0.05
Rifamycin B
Humicola spp.
Localization (protein specific)
intracellular
Humicola spp.
5622
Metals/Ions (protein specific)
additional information
not affected by other metal ions than Fe2+, Hg2+
Humicola spp.
Natural Substrates/ Products (Substrates) (protein specific)
rifamycin B + O2
Humicola spp.
rifamycin O + H2O2
Humicola spp.
?
Purification (Commentary) (protein specific)
partially, ammonium sulfate precipitation
Humicola spp.
Storage Stability (protein specific)
4°C, 100 mM phosphate buffer, pH 7.8, one month, no appreciable loss of actvity
Humicola spp.
Substrates and Products (Substrate) (protein specific)
catechol + O2
439884
Humicola spp.
?
?
p-hydroquinone + O2
439884
Humicola spp.
?
439884
Humicola spp.
?
p-hydroxyphenoxyacetic acid + O2
439884
Humicola spp.
?
?
rifamycin B + O2
439884
Humicola spp.
rifamycin O + H2O2
439884
Humicola spp.
?
rifamycin B + O2
most specific, highest catalytic efficiency
439884
Humicola spp.
rifamycin O + H2O2
439884
Humicola spp.
?
rifamycin SV + ?
439884
Humicola spp.
?
439884
Humicola spp.
?
Temperature Optimum [°C] (protein specific)
45
above the catalytic activity is greatly reduced
Humicola spp.
pH Optimum (protein specific)
Other publictions for EC 1.10.3.6
688670
Jobanputra
-
Influence of nitrogen sources ...
Chryseobacterium sp.
J. Sci. Ind. Res.
66
615-617
2007
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439887
Patil
-
Influence of substrate prepara ...
Curvularia lunata
Indian J. Exp. Biol.
35
917-919
1997
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439886
Banerjee
Transformation of rifamycin B ...
Curvularia lunata
Biotechnol. Tech.
7
339-344
1993
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1
4
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1
1
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439888
Banerjee
Characterization of soluble ri ...
Curvularia lunata
Lett. Appl. Microbiol.
17
1-3
1993
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1
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5
1
1
1
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1
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7
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439883
Vohra
-
Microbial transformation of ri ...
Curvularia lunata
Biotechnol. Lett.
11
851-854
1989
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439884
Seong
-
Enzymatic oxidation of rifamyc ...
Humicola spp.
J. Ferment. Technol.
63
515-522
1985
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3
1
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1
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6
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1
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3
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1
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1
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6
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1
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1
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439885
Lee
-
The properties of immobilized ...
Humicola spp.
Biotechnol. Lett.
6
143-148
1984
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1
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1
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439882
Han
Rifamycin B oxidase from Monoc ...
Monocillium spp.
FEBS Lett.
151
36-40
1983
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