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Literature summary for 1.11.1.11 extracted from

  • Kameoka, T.; Okayasu, T.; Kikuraku, K.; Ogawa, T.; Sawa, Y.; Yamamoto, H.; Ishikawa, T.; Maruta, T.
    Cooperation of chloroplast ascorbate peroxidases and proton gradient regulation 5 is critical for protecting Arabidopsis plants from photo-oxidative stress (2021), Plant J., 107, 876-892 .
    View publication on PubMed
Search for more literature for 1.11.1.11

Protein Variants

Protein Variants Comment Organism
additional information generation of stromal and thylakoid membrane-bound ascorbate peroxidases (sAPX and tAPX, respectively) knockout mutants, exhibiting no visible phenotype under high-light (HL) stress. The Arabidopsis thaliana sapx/tapx double mutant is crossed with a proton gradient regulation 5 (pgr5) single mutant, wherein both DELTApH-dependent mechanisms are impaired. The sapx/tapx/pgr5 triple mutant exhibits extreme sensitivity to HL compared with its parental lines. This phenotype is consistent with cellular redox perturbations and enhanced expression of many oxidative stress-responsive genes. These findings demonstrate that the PGR5-dependent mechanisms compensate for chloroplast APXs, and vice versa. The failure of induction of non-photochemical quenching in pgr5 (because of the limitation in DELTApH formation) is partially recovered in sapx/tapx/pgr5 mutants. This recovery is dependent on the NADH dehydrogenase-like complex-dependent pathway for cyclic electron flow around photosystem I Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Arabidopsis thaliana 9507
-
chloroplast stroma
-
 Arabidopsis thaliana 9570
-
thylakoid membrane membrane-bound Arabidopsis thaliana 42651
-

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ in the heme group Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 L-ascorbate + H2O2 + 2 H+ Arabidopsis thaliana
-
 L-ascorbate + L-dehydroascorbate + 2 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q42592
-
-
Arabidopsis thaliana Q42593
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 L-ascorbate + H2O2 + 2 H+
-
 Arabidopsis thaliana L-ascorbate + L-dehydroascorbate + 2 H2O
-
 ?

Synonyms

Synonyms Comment Organism
APXS gene name, UniProt Arabidopsis thaliana
APXT gene name, UniProt Arabidopsis thaliana
AT1G77490 gene name, UniProt Arabidopsis thaliana
AT4G08390 gene name, UniProt Arabidopsis thaliana
sAPX
-
 Arabidopsis thaliana
stromal ascorbate peroxidases
-
 Arabidopsis thaliana
tAPX
-
 Arabidopsis thaliana
thylakoid membrane-bound ascorbate peroxidases
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
heme
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction stromal and thylakoid membrane-bound ascorbate peroxidases (sAPX and tAPX, respectively) knockout mutants do not exhibit a visible phenotype under high-light (HL) stress. PGR5-dependent mechanisms compensate for chloroplast APXs, and vice versa Arabidopsis thaliana
physiological function stromal and thylakoid membrane-bound ascorbate peroxidases (sAPX and tAPX, respectively) are major H2O2-scavenging enzymes in chloroplasts. PGR5-dependent mechanisms compensate for chloroplast APXs, and vice versa under high-light stress Arabidopsis thaliana