Cloned (Comment) | Organism |
---|---|
expression vector encoding mitochondrial enzyme for overexpression in (RBL)2H3 cell line | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | (RBL)2H3 cell line stably overexpressing mitochondrial phospholipid hydroperoxide glutathione peroxidase from transfected expression plasmid | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + lipid hydroperoxide | Rattus norvegicus | - |
glutathione disulfide + lipid + H2O | - |
? | |
additional information | Rattus norvegicus | mitochondrial enzyme inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukemia cell | basophil leucemia cell line S1 wild-type cell line and (RBL)2H3 cell line overexpressing mitochondrial phospholipid hydroperoxide glutathione peroxidase | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + cardiolipin | - |
Rattus norvegicus | ? | - |
? | |
glutathione + lipid hydroperoxide | - |
Rattus norvegicus | glutathione disulfide + lipid + H2O | - |
? | |
glutathione + tert-butyl hydroperoxide | - |
Rattus norvegicus | ? | - |
? | |
additional information | mitochondrial enzyme inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis | Rattus norvegicus | ? | - |
? |