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Literature summary for 1.11.1.12 extracted from
- Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity (2006), Free Radic. Res., 40, 936-943.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| selenoprotein P | 2 nM, 3fold stimulation of activity after 24h | Homo sapiens | |
| Sodium selenite | 100 nM, 3fold stimulation of activity after 24h | Homo sapiens |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Mercaptosuccinate | 0.1 mM | Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelial cell line | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + tert-butylhydroperoxide | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GPX | - |
Homo sapiens |
| phospholipid hydroperoxide glutathione peroxidase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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