Protein Variants | Comment | Organism |
---|---|---|
Y102F | mutant maintains 60% of the activity of the wild-type enzyme | Streptomyces wedmorensis |
Y103F | mutant maintains 60% of the activity of the wild-type enzyme | Streptomyces wedmorensis |
Y105F | mutant enzyme is inactive | Streptomyces wedmorensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces wedmorensis | Q56185 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | DOPA formation, probably at Tyr105, is a self-hydroxylation reaction | Streptomyces wedmorensis |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
(S)-2-hydroxypropylphosphonate + H2O2 = (1R,2S)-1,2-epoxypropylphosphonate + 2 H2O | Tyr105 is a key residue, which plays a role in the activation of dioxygen required for the enzymatic activity of HppE | Streptomyces wedmorensis |