Literature summary for 1.11.1.23 extracted from

Wang, C.; Chang, W.C.; Guo, Y.; Huang, H.; Peck, S.C.; Pandelia, M.E.; Lin, G.M.; Liu, H.W.; Krebs, C.; Bollinger, J.M.
Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase (2013), Science, 342, 991-995.

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Iron	a non-heme-iron peroxidase	Yersinia pseudotuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
(S)-2-hydroxypropyl-1-phosphonate + H2O2	Yersinia pseudotuberculosis	-	(1R,2S)-1,2-epoxypropylphosphonate + H2O	i.e. fosfomycin	?

Organism

Organism	UniProt	Comment	Textmining
Yersinia pseudotuberculosis	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(S)-2-hydroxypropyl-1-phosphonate + H2O2	-	Yersinia pseudotuberculosis	(1R,2S)-1,2-epoxypropylphosphonate + H2O	i.e. fosfomycin	?

Synonyms

Synonyms	Comment	Organism
(S-HPP) epoxidase	-	Yersinia pseudotuberculosis
fosfomycin-producing epoxidase	-	Yersinia pseudotuberculosis
HppE	-	Yersinia pseudotuberculosis

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Release 2023.1 (January 2023)