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Literature summary for 1.11.1.27 extracted from

  • Kang, S.W.; Baines, I.C.; Rhee, S.G.
    Characterization of a mammalian peroxiredoxin that contains one conserved cysteine (1998), J. Biol. Chem., 273, 6303-6311.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli or in NIH 3T3 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
C47S mutation abolishes peroxidase activity,mutation has no effect on lipase activity Homo sapiens
C91S mutation has no effect on lipase activity Homo sapiens
S32A mutation has no effect on lipase activity Homo sapiens
S32G mutation has no effect on lipase activity Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P30041
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2O2 + dithiothreitol
-
Homo sapiens ?
-
?
additional information the enzyme exhibits a low level of phospholipiase A2 activity at acidic pH Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
1-Cys Prx
-
Homo sapiens