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Literature summary for 1.11.1.8 extracted from
- Purification and properties of an iodide peroxidase from submaxillary gland of goat (1973), Eur. J. Biochem., 37, 541-552.
General Stability
| General Stability | Organism |
|---|---|
| sensitive to pronase treatment | Capra hircus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| azide | - |
Capra hircus |  |
| cyanide | - |
Capra hircus | |
| glutathione | - |
Capra hircus | |
| H2O2 | above 0.00065 mM | Capra hircus | |
| additional information | no inhibition with sulfhydryl reacting reagents and p-chloromercuribenzoate | Capra hircus | |
| thiouracil | - |
Capra hircus | |
| Thiourea | - |
Capra hircus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| iodide + H2O2 | Capra hircus | iodination and coupling reactions of proteins | iodine + H2O | - |
? | |
| iodide + H2O2 | Capra hircus | biosynthesis of thyroid hormones | iodine + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Capra hircus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Capra hircus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| submaxillary gland | - |
Capra hircus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 31 | - |
- |
Capra hircus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| iodide + H2O2 | - |
Capra hircus | iodine + H2O | - |
? | |
| iodide + H2O2 | iodination and coupling reactions of proteins | Capra hircus | iodine + H2O | - |
? | |
| iodide + H2O2 | biosynthesis of thyroid hormones | Capra hircus | iodine + H2O | - |
? | |
| monoiodotyrosine + H2O2 + I- | - |
Capra hircus | monoiodotyrosine + diiodotyrosine + H2O | 90% diiodotyrosine, 6% monoiodotyrosine, determined using radioactive I- | ? | |
| o-dianisidine | - |
Capra hircus | ? | - |
? | |
| tyrosine + H2O2 + I- | - |
Capra hircus | monoiodotyrosine + diiodotyrosine + H2O | ratio 1:4 | ? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | 25 | stable at room temperature at pH 4 for 40 min | Capra hircus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4 | - |
- |
Capra hircus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 2.5 | 7.5 | 20% of activity at pH 2.5, 70% at pH 7.5 | Capra hircus |
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