Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.11.1.9 extracted from

  • Wilkinson, S.R.; Taylor, M.C.; Touitha, S.; Mauricio, I.L.; Meyer, D.J.; Kelly, J.M.
    TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum (2002), Biochem. J., 364, 787-794.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.11.1.9

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Trypanosoma cruzi

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.007
-
 linolenic acid hydroperoxide
-
 Trypanosoma cruzi

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum co-localization with BiP Trypanosoma cruzi 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione + ROOH Trypanosoma cruzi
-
 glutathione disulfide + ROH + H2O
-
 ?
linolenic acid hydroperoxide + GSH Trypanosoma cruzi
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Trypanosoma cruzi

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.13
-
 linolenic acid hydroperoxide Trypanosoma cruzi
0.16
-
 L-alpha-phosphatidylcholine hydroperoxide Trypanosoma cruzi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + ROOH
-
 Trypanosoma cruzi glutathione disulfide + ROH + H2O
-
 ?
L-alpha-phosphatidylcholine hydroperoxide + GSH
-
 Trypanosoma cruzi ?
-
 ?
linolenic acid hydroperoxide + GSH
-
 Trypanosoma cruzi ?
-
 ?