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Literature summary for 1.11.1.9 extracted from

  • Steinbrenner, H.; Bilgic, E.; Alili, L.; Sies, H.; Brenneisen, P.
    Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity (2006), Free Radic. Res., 40, 936-943.
    View publication on PubMed
Search for more literature for 1.11.1.9

General Stability

General Stability Organism
selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Mercaptosuccinate
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenium supplementation by selenoprotein P prevents oxidative damage of human endothelial cells by restoring expression and enzymatic activity of glutathione peroxidase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
EAhy 926 cell human endothelial cell line Ea.hy926 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tert-butyl hydroperoxide + 2 GSH
-
 Homo sapiens tert-butyl alcohol + GSSG + H2O
-
 ?

Synonyms

Synonyms Comment Organism
cGPx
-
 Homo sapiens