Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NADPH | presence of NADPH increases the sulfur reduction activity, but NADPH alone cannot be used as electron donor | Aquifex aeolicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | location of catalytic subunit | Aquifex aeolicus | 5737 | - |
membrane | location of subunit C | Aquifex aeolicus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | sequence is predicted to carry four [4Fe-4S] clusters | Aquifex aeolicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aquifex aeolicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
purification of enzyme by solubilísation with sodium deoxycholate, in presence of ACA and glycerol | Aquifex aeolicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no substrate: dimethyl sulfoxide, thiosulfate. Presence of NADPH increases the sulfur reducing activity. Hydrogenase reaction ond sulfur reduction by enzyme are energetically coupled but take place in two separate complexes. Electron transfer is mediated by quinones | Aquifex aeolicus | ? | - |
? | |
polysulfide + H2 | - |
Aquifex aeolicus | H2S | - |
? | |
S + H2 | - |
Aquifex aeolicus | H2S | - |
? | |
tetrathionate + H2 | - |
Aquifex aeolicus | ? + H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
molybdopterin | - |
Aquifex aeolicus |