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Literature summary for 1.12.99.6 extracted from

  • Pinske, C.; Jaroschinsky, M.; Linek, S.; Kelly, C.L.; Sargent, F.; Sawers, R.G.
    Physiology and bioenergetics of [NiFe]-hydrogenase 2-catalyzed H2-consuming and H2-producing reactions in Escherichia coli (2015), J. Bacteriol., 197, 296-306 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.12.99.6

Activating Compound

Activating Compound Comment Organism Structure
demethylmenaquinone
-
 Escherichia coli
menaquinone
-
 Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
Carbonyl cyanide m-chlorophenylhydrazone
-
 Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Escherichia coli 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2 + 2,3,5-triphenyltetrazolium chloride
-
 Escherichia coli reduced 2,3,5-triphenyltetrazolium chloride
-
 ?
H2 + benzyl viologen
-
 Escherichia coli reduced benzyl viologen
-
 ?
H2 + fumarate
-
 Escherichia coli succinate
-
 ?
additional information the enzyme exhibits both proton-reducing and H2-oxidizing activities Escherichia coli ?
-
 ?

Subunits

Subunits Comment Organism
heterotetramer
-
 Escherichia coli

Synonyms

Synonyms Comment Organism
HybA subunit Escherichia coli
Hyd-2
-
 Escherichia coli
hydrogenase 2
-
 Escherichia coli
[NiFe]-hydrogenase 2
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
iron-sulfur center
-
 Escherichia coli

Expression

Organism Comment Expression
Escherichia coli enzyme synthesis is strongly upregulated during growth on glycerol or on glycerol-fumarate up