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Literature summary for 1.13.11.24 extracted from
- Degradation of rutin by Aspergillus flavus. Studies on specificity, inhibition, and possible reaction mechanism of quercetinase (1972), Can. J. Microbiol., 18, 493-508.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-mercaptoethanol | - |
Aspergillus flavus |  |
| 3-hydroxyflavone | competitive inhibition | Aspergillus flavus | |
| 8-hydroxyquinoline | at 1 mM or more | Aspergillus flavus | |
| alpha-alpha'-dipyridyl | at 1 mM or more | Aspergillus flavus | |
| alpha-naphthoquinoline | - |
Aspergillus flavus | |
| diethyldithiocarbamate | at microM concentrations or less | Aspergillus flavus | |
| Dithiol | at microM concentrations or less | Aspergillus flavus | |
| dithiothreitol | - |
Aspergillus flavus | |
| Dithizone | at microM concentrations or less | Aspergillus flavus | |
| ethylxanthate | competitive inhibition, at microM concentrations or less | Aspergillus flavus | |
| morin | competitive inhibition | Aspergillus flavus | |
| o-phenanthroline | at 1 mM or more | Aspergillus flavus | |
| Quinoline | - |
Aspergillus flavus | |
| Sodium dithionite | - |
Aspergillus flavus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Aspergillus flavus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| quercetin + O2 | Aspergillus flavus | - |
2-protocatechoylphloroglucinolcarboxylate + CO | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus flavus | - |
grown on rutin | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| quercetin + O2 | - |
Aspergillus flavus | 2-protocatechoylphloroglucinolcarboxylate + CO | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00027 | - |
ethylxanthate | - |
Aspergillus flavus | |
| 0.034 | - |
8-hydroxyquinoline | - |
Aspergillus flavus | |
| 0.11 | - |
alpha-naphthoquinoline | - |
Aspergillus flavus | |
| 0.115 | - |
o-phenanthroline | - |
Aspergillus flavus | |
| 0.745 | - |
alpha-alpha'-dipyridyl | - |
Aspergillus flavus | |
| 1.55 | - |
Quinoline | - |
Aspergillus flavus | |
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