Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.13.11.27 extracted from

  • Rundgren, M.
    Some kinetic properties of 4-hydroxyphenylpyruvate dioxygenase from Pseudomonas sp. strain P.J. 874 (1983), Eur. J. Biochem., 133, 657-663.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2-hydroxyphenylacetate product inhibition Pseudomonas sp.
bathophenanthroline
-
Pseudomonas sp.
homogentisate product inhibition Pseudomonas sp.
phenylpyruvate non-competitive inhibition with 4-hydroxyphenylpyruvate as substrate Pseudomonas sp.

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. P.J. 874
-
-
-

Reaction

Reaction Comment Organism Reaction ID
4-hydroxyphenylpyruvate + O2 = homogentisate + CO2 mono-iso-ordered bi-bi mechanism with binding of 4-hydroxyphenylpyruvate before O2 and release of CO2 before homogentisate. A Theorell-Chance mechanism can not be excluded Pseudomonas sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-hydroxyphenylpyruvate + O2
-
Pseudomonas sp. homogentisate + CO2
-
?
4-hydroxyphenylpyruvate + O2
-
Pseudomonas sp. P.J. 874 homogentisate + CO2
-
?
phenylpyruvate + O2
-
Pseudomonas sp. 2-hydroxyphenylacetate + CO2
-
?
phenylpyruvate + O2
-
Pseudomonas sp. P.J. 874 2-hydroxyphenylacetate + CO2
-
?