Literature summary for 1.13.11.27 extracted from

Turick, C.E.; Beliaev, A.S.; Zakrajsek, B.A.; Reardon, C.L.; Lowy, D.A.; Poppy, T.E.; Maloney, A.; Ekechukwu, A.A.
The role of 4-hydroxyphenylpyruvate dioxygenase in enhancement of solid-phase electron transfer by Shewanella oneidensis MR-1 (2009), FEMS Microbiol. Ecol., 68, 223-225.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Shewanella oneidensis

Protein Variants

Protein Variants	Comment	Organism
additional information	construction and complementation of melA mutants of Shewanella oneidensis MR-1, in-frame deletion mutagenesis	Shewanella oneidensis

Inhibitors

Inhibitors	Comment	Organism	Structure
2-(2-chloro-4-methane sulfonylbenzoyl)-1,3-cyclohexanedione	competitive inhibitor	Shewanella oneidensis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4-hydroxyphenylpyruvate + O2	Shewanella oneidensis	-	homogentisate + CO2	-	?
4-hydroxyphenylpyruvate + O2	Shewanella oneidensis MR-1 / ATCC 700550	-	homogentisate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Shewanella oneidensis	Q8EFK9	-	-
Shewanella oneidensis MR-1 / ATCC 700550	Q8EFK9	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-hydroxyphenylpyruvate + O2	-	Shewanella oneidensis	homogentisate + CO2	-	?
4-hydroxyphenylpyruvate + O2	-	Shewanella oneidensis	homogentisate + CO2	homogentisate is an intermediate of the tyrosine degradation pathway, and a precursor of a redox-cycling metabolite, pyomelanin	?
4-hydroxyphenylpyruvate + O2	-	Shewanella oneidensis MR-1 / ATCC 700550	homogentisate + CO2	-	?
4-hydroxyphenylpyruvate + O2	-	Shewanella oneidensis MR-1 / ATCC 700550	homogentisate + CO2	homogentisate is an intermediate of the tyrosine degradation pathway, and a precursor of a redox-cycling metabolite, pyomelanin	?

Synonyms

Synonyms	Comment	Organism
4-HPPD	-	Shewanella oneidensis
4-hydroxyphenylpyruvate dioxygenase	-	Shewanella oneidensis

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Release 2023.1 (January 2023)