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Literature summary for 1.13.11.40 extracted from

  • Yuki, S.; Uemura, A.; Hakozaki, M.; Yano, A.; Abe, M.; Misawa, Y.; Baba, N.; Yamada, H.
    Identification of a novel enzyme from E. pacifica that acts as an eicosapentaenoic 8R-LOX and docosahexaenoic 10R-LOX (2020), Sci. Rep., 10, 20592 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Sf9 cells using a baculovirus expression system Euphausia pacifica

Organism

Organism UniProt Comment Textmining
Euphausia pacifica A0A7G1H6X8 isoform Lox-1
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17S-hydroxy-docosa-4Z,7Z,10Z,13Z,15E,19Z-hexaenoic acid + O2
-
Euphausia pacifica 10R,17S-dihydroxy-docosa-4Z,7Z,11E,13Z,15E,19Z-hexaenoic acid
-
?
arachidonic acid + O2
-
Euphausia pacifica 8R-hydroxy-eicosatetraenoic acid
-
?
docosahexaenoic acid + O2
-
Euphausia pacifica 10R-hydroxy-docosahexaenoic acid
-
?
eicosapentaenoic acid + O2
-
Euphausia pacifica 8R-hydroxy-eicosapentaenoic acid
-
?
additional information LOX1 has higher activity for eicosapentaenoic acid than arachidonic acid and docosahexaenoic acid Euphausia pacifica ?
-
-
stearidonic acid + O2
-
Euphausia pacifica 6-hydroxystearidonic acid
-
?

Subunits

Subunits Comment Organism
? x * 80000, SDS-PAGE Euphausia pacifica

Synonyms

Synonyms Comment Organism
eicosapentaenoic 8R-lipoxygenase
-
Euphausia pacifica
LOX-1
-
Euphausia pacifica

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4 40
-
Euphausia pacifica

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Euphausia pacifica