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Literature summary for 1.13.11.52 extracted from

  • Friberg, M.; Jennings, R.; Alsarraj, M.; Dessureault, S.; Cantor, A.; Extermann, M.; Mellor, A.L.; Munn, D.H.; Antonia, S.J.
    Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection (2002), Int. J. Cancer, 101, 151-155.
    View publication on PubMed
Search for more literature for 1.13.11.52

Inhibitors

Inhibitors Comment Organism Structure
1-Methyltryptophan competitive Mus musculus
additional information inhibition of indoleamine 2,3-dioxygenase may be developed as an anticancer immunotherapeutic strategy Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Trp + O2 Mus musculus enzyme contributes to tumor cell evasion of T cell-mediated rejection L-formylkynurenine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Lewis lung carcinoma cell line
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Trp + O2
-
 Mus musculus L-formylkynurenine
-
 ?
L-Trp + O2 enzyme contributes to tumor cell evasion of T cell-mediated rejection Mus musculus L-formylkynurenine
-
 ?