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Literature summary for 1.13.11.52 extracted from
- In vitro inhibition of rat liver tryptophan oxygenase by 4-hydroxypyrazole (1979), FEBS Lett., 101, 149-152.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 4-Hydroxypyrazole | below 0.1 mM, activation | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-Hydroxypyrazole | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Trp + O2 | - |
Rattus norvegicus | L-formylkynurenine | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
4-Hydroxypyrazole | - |
Rattus norvegicus | |
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