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Literature summary for 1.13.11.52 extracted from
- Expression of rat liver tryptophan 2,3-dioxygenase in Escherichia coli: structural and functional characterization of the purified enzyme (1996), Arch. Biochem. Biophys., 333, 96-102.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Trp + O2 | Rattus norvegicus | key regulatory enzyme, though irreversible degradation, controls the flux of tryptophan through physiologically relevant pathways | L-formylkynurenine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| expression of a fully functional enzyme in Escherichia coli | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Trp + O2 | - |
Rattus norvegicus | L-formylkynurenine | - |
? | |
| L-Trp + O2 | key regulatory enzyme, though irreversible degradation, controls the flux of tryptophan through physiologically relevant pathways | Rattus norvegicus | L-formylkynurenine | - |
? | |
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