KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.44 | - |
D-tryptophan | - |
Micromonospora sp. | |
0.65 | - |
L-tryptophan | - |
Micromonospora sp. | |
2.56 | - |
serotonin | - |
Micromonospora sp. | |
30.27 | - |
indole | - |
Micromonospora sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tryptophan + O2 | Micromonospora sp. | first step during biosynthesis of 3-hydroxyquinaldic acid | N-formyl-L-kynurenine | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Micromonospora sp. | - |
recombinantly expressed in Escherichia coli as a N-terminally His6-tagged protein | - |
Micromonospora sp. ML1 | - |
recombinantly expressed in Escherichia coli as a N-terminally His6-tagged protein | - |
Purification (Comment) | Organism |
---|---|
- |
Micromonospora sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-tryptophan + O2 | - |
Micromonospora sp. | N-formyl-D-kynurenine | - |
ir | |
D-tryptophan + O2 | - |
Micromonospora sp. ML1 | N-formyl-D-kynurenine | - |
ir | |
indole + O2 | - |
Micromonospora sp. | ? | - |
? | |
indole + O2 | - |
Micromonospora sp. ML1 | ? | - |
? | |
L-tryptophan + O2 | - |
Micromonospora sp. | N-formyl-L-kynurenine | - |
ir | |
L-tryptophan + O2 | first step during biosynthesis of 3-hydroxyquinaldic acid | Micromonospora sp. | N-formyl-L-kynurenine | - |
ir | |
L-tryptophan + O2 | - |
Micromonospora sp. ML1 | N-formyl-L-kynurenine | - |
ir | |
additional information | TioF is completely inactive towards tryptamine, 5-hydroxy-L-Trp, and indole propionic acid | Micromonospora sp. | ? | - |
? | |
additional information | TioF is completely inactive towards tryptamine, 5-hydroxy-L-Trp, and indole propionic acid | Micromonospora sp. ML1 | ? | - |
? | |
serotonin + O2 | - |
Micromonospora sp. | ? | - |
? | |
serotonin + O2 | - |
Micromonospora sp. ML1 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TioF | - |
Micromonospora sp. |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0068 | - |
D-tryptophan | - |
Micromonospora sp. | |
0.028 | - |
serotonin | - |
Micromonospora sp. | |
0.045 | - |
L-tryptophan | - |
Micromonospora sp. | |
0.248 | - |
indole | - |
Micromonospora sp. |