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Literature summary for 1.13.11.52 extracted from

  • Johnson, B.A.; Kahler, D.J.; Baban, B.; Chandler, P.R.; Kang, B.; Shimoda, M.; Koni, P.A.; Pihkala, J.; Vilagos, B.; Busslinger, M.; Munn, D.H.; Mellor, A.L.
    B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase (2010), Proc. Natl. Acad. Sci. USA, 107, 10644-10648.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + O2 Mus musculus
-
 N-formyl-L-kynurenine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:CD19+ cell IDO-competent cells exhibit attributes of B cells as well as dendritic cells Mus musculus
-
dendritic cell
-
 Mus musculus
-
splenocyte IDO-competent cells are present in spleens of B-cell-deficient mice Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + O2
-
 Mus musculus N-formyl-L-kynurenine
-
 ?

Synonyms

Synonyms Comment Organism
IDO
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
heme
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus treatment of Pax5iGFP/iGFP knockin mice with CpG oligonucleotides (CpG B 1826 with a fully phosphorothioate backbone, 0.1 mg, i.v.) induces IDO expression up