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Literature summary for 1.13.11.52 extracted from

  • Yan, M.L.; Wang, Y.D.; Tian, Y.F.; Lai, Z.D.; Yan, L.N.
    Inhibition of allogeneic T-cell response by Kupffer cells expressing indoleamine 2,3-dioxygenase (2010), World J. Gastroenterol., 16, 636-640.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.13.11.52

Inhibitors

Inhibitors Comment Organism Structure
1-methyl-tryptophan
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan + O2 Mus musculus
-
 N-formyl-L-kynurenine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Kupffer cell
-
 Mus musculus
-
lymphocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan + O2
-
 Mus musculus N-formyl-L-kynurenine
-
 ?

Synonyms

Synonyms Comment Organism
IDO
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus treatment with interferon-gamma (200 units/ml) induces expression of IDO up

General Information

General Information Comment Organism
physiological function IDO is a mechanism for Kupffer cells to induce immune tolerance Mus musculus