Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1-S-octyl-beta-D-thioglucopyranoside | detergent required, maximal activity at 1% w/v | Homo sapiens | |
octyl beta-glucoside | detergent required | Homo sapiens | |
SDS | detergent required, low activation | Homo sapiens | |
sodium cholate | detergent required | Homo sapiens | |
Triton X-100 | detergent required | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression by an baculovirus/Spodoptera frugiperda 9 insect cell system | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,2'-dipyridyl | - |
Homo sapiens | |
PCMB | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0071 | - |
beta-carotene | - |
Homo sapiens | |
0.03 | - |
beta-cryptoxanthin | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
230000 | - |
gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-carotene + O2 | Homo sapiens | the enzyme catalyzes the first step in the synthesis of vitamin A from dietary carotenoids. May also play a role in peripheral vitamin A synthesis from plasma-borne provitamin A carotenoids | retinal | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9HAY6 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | high levels of BCO mRNA, highest level in jejunum | Homo sapiens | - |
kidney | high levels of BCO mRNA | Homo sapiens | - |
liver | high levels of BCO mRNA | Homo sapiens | - |
ovary | low levels of BCO mRNA | Homo sapiens | - |
prostate gland | low levels of BCO mRNA | Homo sapiens | - |
skeletal muscle | low levels of BCO mRNA | Homo sapiens | - |
testis | low levels of BCO mRNA | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-carotene + O2 | the enzyme catalyzes the first step in the synthesis of vitamin A from dietary carotenoids. May also play a role in peripheral vitamin A synthesis from plasma-borne provitamin A carotenoids | Homo sapiens | retinal | - |
? | |
beta-cryptoxanthin + O2 | - |
Homo sapiens | ? | - |
? | |
beta-cryptoxanthin + O2 | - |
Homo sapiens | all-trans-retinal + ? | - |
r |
Subunits | Comment | Organism |
---|---|---|
tetramer | - |
Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
BCO | - |
Homo sapiens |
beta-carotene 15,15'-monooxygenase | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.011 | - |
beta-carotene | - |
Homo sapiens | |
0.668 | - |
beta-cryptoxanthin | - |
Homo sapiens |