Cloned (Comment) | Organism |
---|---|
gene PA4202 or nmoA, monocistronic, low expression level gene, has an intergenic region of 97 nucleotides with neighbouring gene PA4201 (ddlA) encoding D-alanine alanine ligase, and an intergenic region of 107 nucleotides with gene PA4203 encoding a LysR regulator, PA4203 (nmoR) represses its own transcription and the expression of PA4202 (nmoA), presence of a single NmoR binding site between nmoA and nmoR, and interaction of NmoR with the intergenic nmoA-nmoR control region. In silico analysis of the ddlA-nmoA-nmoR-ppgL locus in Pseudomonas aeruginosa genomes, transcriptome analysis | Pseudomonas aeruginosa |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of an enzyme deletion mutant by the in vivo recombination system of the yeast Saccharomyces cerevisiae strain InvSc1, overview. Quantitative RT-PCR enzyme expression analysis. The expression of ddlA is not changed in the DELTAnmoA mutant compared to the wild-type | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 propionate-3-nitronate + O2 | Pseudomonas aeruginosa | - |
3 malonic semialdehyde + nitrite + 2 nitrate + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | Q9HWH9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3 propionate-3-nitronate + O2 | - |
Pseudomonas aeruginosa | 3 malonic semialdehyde + nitrite + 2 nitrate + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nitropropane dioxygenase | - |
Pseudomonas aeruginosa |
nmoA | - |
Pseudomonas aeruginosa |
P3N monooxygenase | - |
Pseudomonas aeruginosa |
PA4202 | - |
Pseudomonas aeruginosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | a flavoprotein | Pseudomonas aeruginosa |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of the nmoA gene results in an increased sensitivity of the cells to 3-nitropropionic acid (3-NPA), phenotype, overview | Pseudomonas aeruginosa |
physiological function | role of the nitronate monooxygenase protein in the detoxification of nitronate. At physiological pH, 3-nitropropionate, a nitro toxin produced by plants and fungi, exists in equilibrium with its conjugate base, propionate-3-nitronate, the tauromer of 3-nitropropionic acid | Pseudomonas aeruginosa |